- Malattie cardiache
- Parkinson
- GvHd
- Lesioni spinali
- Ictus cerebrali
- Degenerazione dei nuclei della base (MSA, PSP, Huntington, Tourette)
- Alzheimer
- Malattie autoimmuni
- Danni renali
- Sclerosi multipla
- Diabete Mellito di tipo I
- Osteogenesi Imperfetta e difetti osseo-cartilaginei
- Lupus eritematoso sistemico
- Transplantologia
Un blog dedicato alle cellule staminali e al loro utilizzo terapeutico.
Interviste, analisi e articoli scritti dai sostenitori della Stamina Foundation.
Su quali patologie opera la medicina rigenerativa?
5) Trapianto di cellule staminali per la cura della sclerosi multipla
J Neurol. 2008 Dec;255 Suppl 6:43-7.
Stem cell transplantation in multiple sclerosis.
Schippling S, Heesen C, Zander A, Martin R.
Institute of Neuroimmunology and Multiple Sclerosis Research (INiMS), Center of Molecular Neurobiology, Falkenried 3, 20246 Hamburg, Germany. [email protected]
Abstract
Following promising results in animal studies showing that immunosuppression and consecutive allogeneic bone marrow transplantation has the potential to significantly reduce autoimmunity, emerging data is supporting a benefit in patients with multiple sclerosis (MS) and other autoimmune disorders not responding to approved therapies. Until today, results on over 400 cases have been reported by the European Blood and Marrow Transplantation Group (EBMT), many of them with a favorable outcome. However, results of randomized, controlled clinical trials are missing. Furthermore, with upcoming new treatment compounds that to some extent act via lymphoablative properties, it remains essential to better select those patients who might profit most from stem cell therapy based on a justifiable benefit-to-risk ratio.
